everything
genetic
Available at The Private GP Group
Why The Private GP Group work with Everything Genetic…
Everything Genetic offer:
- Pre and post-test clinical support, scalable through use of digital technologies.
- A consultative approach to genetic testing that educates, informs and supports healthcare providers and businesses.
- Testing technology that meets rigorous independent standards and clinical expertise.
- A disruptive pricing strategy to ensure testing is affordable for all.
- A custom-built, secure online portal for ordering, patient management and reporting.
- In-house customer care, logistics and technical team that provides a best-in-class and-to-end service.
One in three men and one in four women develop cancer in their lifetime. Our individual cancer risk can be very high, whether or not there is a family history of cancer.
Everything Genetics’ quick and easy to use home test kits provide personalised test results of your cancer risk score and likelihood of disease in the next 10 years.
Everything Genetic provide wrap-around clinical support ensureing that everyone taking a genetic risk test understands the implications of the result and what action to take.
Too many cancers are currently diagnosed at an advanced stage. Knowing the personal cancer risks of individuals is the key to better cancer prevention and longevity.
What tests are available?
Multi-Cancer Panel
Price of test: £399
The Everything Genetic Multi-Cancer Panel is a genetic test comprising of a panel of 72 genes which has been uniquely designed to help individuals understand their risk of developing hereditary cancers; preventing disease onset and reducing the impact through early detection. It identifies the presence of germline variants – the genes that are known to increase the risk of specific types of cancer.
This panel is suitable for individuals:
– Who do not have symptoms or a diagnosis of cancer, with or without a known family history of cancer or
– Cancer patients to help inform screening, prevention, and treatment decisions or
– Immediate at-risk relatives of individuals with an identified genetic mutation in one or more of the following familial cancers:
Breast | Ovarian | Colorectal |
Melanoma | Thyroid | Pancreatic |
Prostate | Gastric | Renal |
Endometrial | Uterine | Skin |
This test is only suitable for persons aged 18+.
This panel represents the most common cancers found in the UK and individuals may have increased risk of these cancers, whether there is a known history of cancer in your family or not. Knowing your personal cancer risk is the key to cancer prevention and longevity.
It’s important to remember that cancers are not only caused by hereditary faults: lifestyle, environment and age can all play a part.
If you do notice anything unusual about your health, it is recommended you seek advice from your clinician or GP.
This test does not tell you if you have cancer.
The Everything Genetic Multi-Cancer Panel is a simple saliva test which can be taken in the comfort of your own home and once the sample has arrived at the laboratory in the UK it should provide a report within 2-3 weeks.
There is pre and post-test clinical support provided to explain what the test is for and also to help you understand the results. Pre-test clinical support is provided by an informational video with the option to arrange a call with a genetic expert if required.
Post-test clinical support for patients with a negative and VUS result is provided by an informational video with the option to arrange a call with a genetic expert if required. For patients with a positive result, clinical support is provided by a genetic expert by a pre-arranged private consultation. An individual will not receive any results or report until this consultation has taken place.
All pre and post-test clinical support is included in the test kit price.
The report will show one of three different outcomes: Negative, Positive and VUS.
- Negative (no genetic variants have been identified in the genes tested)
- Positive (a genetic variant has been identified in the genes tested that are associated with a high to moderate increased risk of cancers tested for)
- Variant of Unknown Significance (VUS) (This test did not identify any genetic variants but includes at least one result that is not completely understood at this time. Please note that the classification of variants may change over time as a result of new variant interpretation guidelines and/or new information. If a VUS is reclassified, Everything Genetic will update this report with the new interpretation and provide notification directly).
12 Gene Breast Cancer Panel
Price of test: £299
If you are a patient who has already been diagnosed with breast cancer, the Everything Genetic 12 Gene Breast Cancer Panel test quickly assesses your risk of developing the cancer in the other breast or ovaries. It is designed for patients awaiting time-sensitive surgery or treatment decisions, and those being considered for PARP inhibitor drug therapies.
Even if you have undergone chemotherapy treatment or surgery to remove a tumour, and scans have shown that the cancer cells have been eradicated, genetic mutation carriers can still have a significantly increased risk of developing breast or ovarian cancer as a second primary.
By analysing 12 well-established genes associated with a significantly increased risk of breast and ovarian cancer, including the BRCA1 and BRCA2 genes, this test provides clinically actionable results to help you and your clinician to create a personalised screening, prevention, and treatment plan.
Genes analysed:
ATM | CDH1 | RAD51C |
BARD1 | CHEK2 | RAD51D |
BRCA1 | PALB2 | STK11 |
BRCA2 | PTEN | TP53 |
Some people have an increased risk of a particular type of cancer because they have inherited a genetic mutation. They can be passed on from parent to child.
A child of a parent who carries a genetic mutation has a 50% chance (or 1 in 2) of inheriting it too.
This test is specifically designed for detecting hereditary genetic mutations, making it suitable for testing your immediate relatives. It will show if they are carrying a genetic mutation that may increase their risk of developing breast and ovarian cancer, enabling them to make proactive healthcare decisions to prevent or treat the disease.
The test includes pre and post-test clinical support, helping you to understand:
- What the test is for
- Why you should take the test
- What it does and doesn’t test for
- What the possible results are from taking the test
- And, once the results report is available, what the result mean and next steps.
Pre and post-test clinical support is provided by informational videos with the exception of private consultations for positive patients.
Positive result:
- A genetic mutation has been found in one or more of the genes analysed.
- You are therefore at a higher risk of developing the cancer(s) that the gene increases.
- This may mean eligibility for MRI screening of the breast (BRCA1, BRCA2, PALB2, STK11, CDH1, PTEN) or risk-reducing surgery.
- It provides a definitive test that relatives can be tested for on the NHS.
Negative result:
- No genetic mutations have been found in the genes analysed.
- Not all cancers can be attributed to genetic mutations, the environment, lifestyle, and age can also have an effect.
- Overall, in most instances your risk of further cancer are reduced in the breast and ovaries with ovarian risk usually returning to population levels.
Variant of unknown significance result:
- Also known as a VUS, the test has identified a change in the sequence of one of your genes, but it is not yet known if that indicates a clinically significant breast cancer risk.
- Most VUS results are eventually reclassified as harmless.
- It is, however, unusual to receive a VUS result on any of these genes.
Antegenes
Antegenes analyses thousands of genetic variants to help men an women understand their risk of developing common cancers including breast, prostate, colorectal and melanoma.
AnteBC
Price of test: £200
A genetic risk test for breast cancer. Recommended for women aged 30-75.
AntePC
Price of test: £200
A genetic risk test for prostate cancer. Recommended for men aged 40-70.
AnteCRC
Price of test: £200
A genetic risk test for colorectal cancer. Recommended for women and men aged 40-75.
AnteMEL
Price of test: £200
A genetic risk test for melanoma. Recommended for women and men aged 18-70
AnteCancerM
Price of test: £250
A set of tests for men, includes prostate, colorectal cancer, and melanoma tests. Recommended for men aged 40-70.
AnteCancerW
Price of test: £250
A set of tests for women, includes breast, colorectal cancer, and melanoma tests. Recommended for women aged 35-70.